Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is the most frequent inborn error of metabolism, and accounts for 90-95% of CAH cases.The affected enzyme, P450C21, is encoded by the CYP21A2 gene, located together with a 98% nucleotide sequence identity CYP21A1P pseudogene, on chromosome 6p21.3.Even though most patients carry C
Training educators and learners in person-centred, solution-orientated coaching approaches may facilitate the development of a learner-centred mindset.Imperial Handheld Games College London developed a Massive Open Online Course (MOOC) in coaching skills for learner-centred conversations.A mixed methodology (post-course survey and semi-structured i
Health inequalities refer to systematic, unfair and avoidable differences in health across the population and between different groups in society.We reviewed health inequalities related to breast cancer to inform National Institute for Health and Care Excellence (NICE) recommendations.This was a pragmatic, targeted review to identify examples of he
We evaluate the configuration exponents of various ensembles of Hamiltonian paths drawn on random planar bicubic maps.These exponents are estimated from the extrapolations of NiCd Portable Phone Battery exact enumeration results for finite sizes and compared with their theoretical predictions based on the Knizhnik, Polyakov and Zamolodchikov (KPZ)
Many sentiment analysis methods have been proposed recently to evaluate, through the Web, the perceptions of users and their satisfaction with the use of products and services; these approaches have been applied in Console various fields in which it is necessary to evaluate, for example, the degree of appreciation of a product or a service or polit